Exploiting Public Metagenomic Data to Uncover Cancer-Microbiome Relationships
This site automatically tracks GitHub repositories associated with NCI grant R01CA230551 to the CUNY Graduate School of Public Health and Health Policy.
- PI: Levi Waldron
- co-Investigators: Curtis Huttenhower, Nicola Segata, Sean Davis
Public Health Relevance
The human microbiome is implicated in the development and response to treatment of some cancers, including infectious agents estimated to be responsible for ~20% of the global cancer burden. However, previously unrecognized bacterial and viral strains, as well as loss of normal structure and function of human-associated microbiomes, likely play additional roles in disease etiology and treatment. This project investigates the role of the human microbiome in cancer by applying novel and state-of-the-art methods to published metagenomic data, and provides enhanced, expanded, and more efficiently usable microbiome data resources back to the cancer research community for a broad range of investigations.